Pricing · effective 2026-04-29MONTHLY·ANNUAL−17%Jump to compare ↓

Pricing that fits how science actually runs.

Free for iGEM and academics, forever. Pro is a flat $299/mo plus pennies per seed. Frontier is annual, invoiced, with a named account lead. That’s it.

Beta access · Free tier no-cost until 2026-06-01
§ 05 — Pricing

Three folds. No surprises.

Free tier is free, forever. Pro is a flat subscription plus metered compute. Frontier is annual, invoiced, with a named account lead. That’s it.

Free
$0forever
For iGEM teams · students · academics
  • Every open-source tool
  • Bring your own compute
  • Public leaderboard access
  • Community support
  • 7-day data retention
Start free
Most chosen
Pro
$299/ month
For Labs · core facilities · biotech
  • Managed GPU, metered
  • 50,000 seeds / month
  • Private campaigns
  • Priority queue
  • Email support · 24h
  • 90-day retention
Start 14-day trial
Frontier
$50K+/ year
For Pharma · Series B+ biotech
  • Closed frontier models
  • Dedicated cluster
  • VPC or on-prem deploy
  • Custom tool integration
  • Shared Slack · 1h SLA
  • SOC 2 · HIPAA eligible
Talk to us
Feature matrix

Everything in one table. No legal-team translation required.

Feature matrix
Free
$0
Pro
$299 /mo
Frontier
$50K+ /yr
Volume
Seeds / month included
500
50,000
Unlimited (1M soft cap)
Max concurrent jobs
2
20
200
Seats / org
1
10 (+$50/seat)
Unlimited
Job retention
7 days
90 days
365 days or custom
Tools & Compute
Open-source tools (RFdiffusion, BindCraft, Boltz-2, Chai-1, MPNN…)
Closed-weight models (AF3-Pro, internal diffusion)
Compute
BYOC only
Managed A100/H100
Dedicated cluster
Top-up packs
N/A
VPC / on-prem deploy
Support & Compliance
SLA
99.5% best-effort
99.9% contractual
Support
Community
Email · 24h
Shared Slack · 1h
MSA / DPA / BAA
Standard ToS
Custom signed
SOC 2 · HIPAA-eligible
In progress

* Source: docs/plans/05-billing-pricing.md §1

Not sure which fold?

Start free. Upgrade when you outgrow it.

Pharma teams: Frontier ships annual, invoiced, with a named account lead. Contracts start at $50K.

  • ·BAA · HIPAA-ready
  • ·99.9% SLA
  • ·SSO · SCIM
  • ·Audit retention 7y
  • ·Dedicated support
  • ·BYOC · on-prem
§ Pricing FAQ6 questions

Billing, specifically.

What does "beta access" mean during launch?
Through 2026-06-01, every account runs on the Free tier with Pro-level seed quotas unlocked, no card required. We collect telemetry (with your opt-in) to harden the orchestrator before GA. Pro and Frontier billing only switch on after 2026-06-01, and existing beta accounts get their first month free at the published rate.
How does seed metering work?
A seed counts when the orchestrator emits seed.completed (success OR graceful failure). Crashes in the first 30s do not count. Idempotency keys deduplicate retries within 24h. Real-time enforcement, daily roll-up for billing.
What happens if I exceed my Pro cap?
Your dashboard meter turns yellow at 80%, red at 95%. You can either (a) buy a top-up pack — 10k seeds for $99, 50k for $399 — or (b) opt into overage at $0.012/seed, billed end of month. Default is block, not overage.
Do you offer an annual discount?
Yes. Pro annual is $2,990 (17% off, two months free). Frontier is annual-only by default, with quarterly available on request. Standard net-30, net-60 negotiable above $150K.
What's the support response time?
Free is community Discord, no SLA. Pro is email at hello@papercrane.bio with 24h response 9am-9pm PT M-F. Frontier is shared Slack with 1h response and an on-call rotation for P0 incidents.
Can I bring my own GPUs?
Free requires it — runs entirely on your hardware. Pro lets you mix managed and BYOC. Frontier is most often BYOC into pharma's existing A100 fleet, with a 0% markup; we just charge the platform fee.
§ 07 — Questions

The answers to the questions.

Free is free forever on your own hardware. Pro is a flat monthly subscription plus metered compute (pennies per seed). Frontier is annual, invoiced, with a dedicated account manager.

Every major open-source tool: ProteinMPNN, RFdiffusion, BindCraft, Chroma, Genie2, LigandMPNN, ESM-IF, BoltzDesign, plus validators (AF3, Boltz-2, Protenix, Chai-1). Closed partners available on Frontier.

Yes. On Pro, your inputs and outputs are encrypted at rest and never used for training. On Frontier we deploy into your VPC — we never see your data. Free tier runs on your own hardware, so privacy is yours.

Yes. Open a PR on our catalog repo with a Dockerfile and a benchmark run. We review weekly. Frontier customers get white-glove integration of proprietary tools.

Pro and Frontier are SOC 2 Type II (in progress) and HIPAA-eligible. All traffic TLS 1.3, storage AES-256, compute in sandboxed containers. Frontier deploys within your cloud account.

No. Your designs are yours. We don't own them, license them, or patent them. We're a platform, not a partner on your IP.